- Gigantism (Disproportionate) compare to Familial Tall Stature (Proportionate)
- Acromegally is associated with colonic polyposis or cancer colon **one of the causes of death in them
- The best initial screening test for acromegaly is measuring serum IGF-1 ((most reliable test))
- For confirmation of acromegally ( glucose suppression test )
- WHY is Glucocorticoids (ACTH)must be replaced before Thyroxine in patients with Panhypopituitarism.?? Thyroxine increases the metabolic rate and clearance of cortisol. If thyroxine is given to a patient with cortisol deficiency before glucocorticoid replacement, it can precipitate acute adrenal crisis....addisonion crisis
- Monitoring of thyroid hormone replacement in secondary hypothyroidism relies on measuring Free T4 levels, not TSH.
- اي سبب ال pallor ؟ نقص ال ACTH in secoundery hypoadrenalism ، وبيحصل كمان مع hypogonadism بسبب نقص testosterone
- في panhypopituitarism اول هرمون بيقل هو ال GH لكن اعراضه مبتكنش واضحه ، لكن اول presentation is faliuer of lactation
- The most effective treatment for growth hormone-secreting pituitary adenomas is transsphenoidal surgery.