Type I Hypersensitivity	Type IV Hypersensitivity
Occurs within minutes after exposure	Occurs 36-72 hours after exposure
IgE-mediated	Cell-mediated (no antibody involvement)
Involves mast cells, basophils, and soluble mediators	Involves sensitized memory T cells (Th1, Th2, Tc) and macrophages
Manifestations: urticaria, asthma, rhinitis, anaphylaxis	Manifestations: contact dermatitis, graft rejection, granuloma formation, intracellular infections
Diagnosed by skin prick tests and serum IgE levels	Diagnosed by delayed skin tests (e.g., tuberculin test)

","creatorId":93,"createdAt":null,"updatedAt":"2025-08-23T18:56:41.369Z"} 34:["$35","$36","$37"] 31:{"id":1912,"quizId":278,"image":null,"width":null,"height":null,"creatorId":93,"createdAt":null,"updatedAt":"2025-08-23T18:56:41.322Z","tapes":"$32","masks":"$33","subQuestions":"$34"} 39:[] 3a:[] 3c:{"id":4189,"questionId":1909,"text":"[Case] A patient develops fever, urticaria, arthralgia, splenomegaly, lymphadenopathy, and glomerulonephritis approximately 10 days after receiving a single large injection of foreign serum antitoxin. What is this condition?","answer":"

Serum sickness, a generalized form of Type III hypersensitivity reaction.

","creatorId":93,"createdAt":null,"updatedAt":"2025-08-23T18:56:41.343Z"} 3d:{"id":4193,"questionId":1909,"text":"A Rh-negative mother delivers her first Rh-positive baby. What preventive measure should be taken within 72 hours after delivery to prevent hemolytic disease of the newborn in future pregnancies?","answer":"

Passive immunization of the mother with anti-Rh antibodies to destroy the Rh+ cells of the baby that passed the placenta and prevent sensitization of the mother.

","creatorId":93,"createdAt":null,"updatedAt":"2025-08-23T18:56:41.343Z"} 3e:{"id":4194,"questionId":1909,"text":"A patient develops edema, erythema, and hemorrhagic necrosis at the sit

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