5th Semester → CNS🦋 Biochemistry

L1&2) Neurotransmitters

L1 Bio notes for MCQs

ا✍الانزيم ال بيعمل acetylcholine اسمه

choline acetyletransferase

ا✍الانزيم ال بيعمل GABA اسمه Glutamate decarboxylase

✍GABA بيعمل convulsions in children

✍ Serotonin = happy chemical

✍Most abundant neurotransmitter 👉 acetylcholine

ا✍ الدوبامين بناخده دايركت من tyrosine و indirect من phenylalanine

✍antidote for organophosphorus poisoning 👉 atropine (بيمسك في الريسبتورز بتاعت الاستيلكولين)

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L2 Bio notes for MCQs

✍neuropeptides responsible for slow onset long lasting (ممكن يلعب فيها امسيكيو ) modulation of synaptic transmission

✍ active form of G-protein 👉 Alpha subunit+ GTP

✍ excitatory neurotransmitter of pain impulses👉 substance P

✍ precursor protein of endorphins👉 pro-opiomelanocortin (POMC)

✍ enkephalins 👉 pentapeptide

✍ somatostatin 👉 synthesized in D-cells of pancreas .. decreases gastric and digestive secretions

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Written of L1

.Definition of neurotransmitters

. Classification ( function, strucure)

. Synthesis and degradation of Acetylcholine / Gaba

. Function of Ach

.  Role of Atropine as an antidote

. Site of serotonin, why it is used in depression ttt

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Written of L2.

mechanism of action of nueropeptides .

Forms of G ptn .

Types of endogenous opoid peptides.

Synthesis of endorphins .

function of somatostatin.